Friday 19 September 2014

DEVIATION FROM MENDEL'S LAW OF INHERITANCE



Allelic interactions Dominance is sometimes incomplete. In such cases heterozygotes (progeny) show intermediate between those of two homozygotes (parents), the gene is said to be governed by incomplete dominance. Sometime, the two alleles at a locus produce two different phenotypes that both appear in heterozygotes, a phenomenon called co-dominance e.g., ABO blood group in human. Some alleles have multiple phenotypic effects, the allele is called pleiotropic.

Non-allelic interactions    Different genes also interact and affect the expression each other in many different ways. Such interactions are also called non-allelic interaction. One interaction where one gene affects the expression of another gene is called epistasis. The gene which is expressed is known as epistatic and the gene whose expression is masked is known as hypostatic. The most challenging problem is the expression of complex phenotypes that are caused by many interacting genes and the environment.

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