This immune system normally displays recognition of the "self" from "non"-self" (or foreign) known as immunologic tolerance, i.e., the immune system can recognize its own cells, tissues or chemicals from an outsider (foreign protein or the foreign antigen).
Hence, it does not produce "T" or "B" cells against them. But, sometimes this sensibility is lost and it fails to discriminate between its own and foreign antigens. this loss of immunologic tolerance results in autoimmune diseases, where immune response mediated by antibodies is produced against its own tissues or antigens.
Hence, it does not produce "T" or "B" cells against them. But, sometimes this sensibility is lost and it fails to discriminate between its own and foreign antigens. this loss of immunologic tolerance results in autoimmune diseases, where immune response mediated by antibodies is produced against its own tissues or antigens.
Some of such diseases are Type-I diabetes mellitus, multiple sclerosis, rhematoid arthritis, thyroiditis,rheumatoid fever, hemolytic and pernicious anemia and myasthenia gravis (the disease which affects our superstar Amitabh Bachchan)
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