Friday 5 December 2014

PRACTICAL APPLICATIONS OF DNA TECHNOLOGY




1. Use of Recombinant DNA technology  to identify human genes, particularly the defective genes that cause human diseases viz Humingtom diseases, cystic fibrosis etc.

2.Molecular diagonals of human diseases. The mutant goes responsible for several inherited human diseases can be accurately diagnosed by screening genomic DNAs and results of these tests can then be used by genetic counselors to inform about the risks.

3. Human Gene Therapy - this involves the addition of a normal (wild-type) copy of a gene to the genome of an individual who carries defective copy of the gene, e.g. somatic cell gene therapy for patients with adenosine dreaminess-deficient severe combined immunodeficiency disease (Ada-SCID)
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4. Transgenic Plants and Animals (already discussed in detail)

In 1995, Kary Mullis developed a technique called the polymerase chain reaction (PCR) that produces millions of copies of DNA from a minute amount of a selected DNA sequence for molecular analysis.

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